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Here's what the clinical research supports for each common health goal

Caffeine, through A 1 and A 2A receptor antagonism, is involved in the control of synaptic transmission and plasticity, which may be related to its neuroprotective effect [95]

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Both trials employed a Mexameter MX 18 (Courage+Khazaka electronic GmbH, Cologne, Germany) to evaluate the primary efficacy outcome